1. Detail the historical evolution of graduate medical education (GME), specifically residency programs, in the U.S., including their origins, significant changes, funding mechanisms, and challenges faced throughout different periods.

2. Elaborate on the various classifications of medical residency programs in the U.S., distinguishing between categorical, preliminary/transitional, and advanced positions, and provide specific examples of their typical durations for different specialties, including subsequent fellowship training options.

3. Analyze the historical and contemporary similarities and differences between allopathic (M.D.) and osteopathic (D.O.) physicians in the U.S., considering their training, philosophical approaches, licensing, residency experiences, and patient care practices.

4. Discuss the origins, key recommendations, and far-reaching impacts of the 1910 Flexner Report on American medical education, including its influence on medical school standards, curriculum, institutional affiliations, faculty roles, and its enduring legacy, as well as any criticisms or unintended consequences.

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